Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Venous Return01:04

Venous Return

4.2K
The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
4.2K
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

1.4K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.4K
Weightlessness01:01

Weightlessness

5.0K
When an object is dropped, it accelerates toward the center of the Earth. If the net external force on the object is its weight, it is said to be in free fall; that is, the only force acting on the object is gravity. Galileo was instrumental in showing that, in the absence of air resistance, all objects fall with the same acceleration g. However, when objects on the Earth fall downward, they are never truly in free fall, because there is always some upward resistance force from the air acting...
5.0K
Assessment of the Cardiovascular System III: Palpation01:27

Assessment of the Cardiovascular System III: Palpation

326
Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
326
Pressure Relationships in Thoracic Cavity01:24

Pressure Relationships in Thoracic Cavity

2.3K
Breathing, otherwise known as pulmonary ventilation, is the process of air movement into and out of the lungs. The main mechanisms propelling pulmonary ventilation are atmospheric pressure (Patm), intra-pulmonary (Ppul ) or intra-alveolar pressure (Palv) within the alveoli, and intrapleural pressure (Pip) within the pleural cavity.
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs...
2.3K
Pressure Variation in a Fluid at Rest01:11

Pressure Variation in a Fluid at Rest

253
In a fluid at rest, the pressure at any point beneath the fluid surface depends solely on the depth, not on the container's shape or size. This principle, known as hydrostatic pressure, arises because, in stationary fluids, there is no acceleration, meaning the forces within the fluid balance out. Only vertical forces, caused by the weight of the fluid above, contribute to pressure changes with depth.
When measuring pressure at two different levels within the fluid, the difference in...
253

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

pVACtools v6: A comprehensive suite for neoantigen prediction, visualization, and therapy design.

ArXiv·2026
Same author

Repeat Exposures to Spaceflight or Bed Rest and Spaceflight-Associated Neuro-Ocular Syndrome Findings.

JAMA ophthalmology·2026
Same author

Individualised N-terminal Pro-B-type Natriuretic Peptide Thresholds for the Diagnosis of Heart Failure: A Proof-of-Concept Study.

Cureus·2026
Same author

Effects of Artificial Gravity on the Vascular System during 60 days of Strict Head-Down Tilt Bedrest.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same author

Long-read cDNA sequencing reveals novel isoforms and spliceosome-mutant-enriched transcripts in AML and MDS.

bioRxiv : the preprint server for biology·2026
Same author

Cardio-oncology research prioritisation in the United Kingdom: national surveys of health care professionals, patients and carers.

Cardio-oncology (London, England)·2026
Same journal

Thoroughbred horses susceptible to Recurrent Exertional Rhabdomyolysis have elevated skeletal muscle mitochondrial capacities.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Change in Neutrophil-to-Lymphocyte Ratio after acute and chronic exercise: A Systematic Review and Meta-Analysis.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Ankylosing spondylitis and muscle sympathetic nerve activity: a case study.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Intracranial vasomotor and blood flow responses to light intensity aerobic exercise in young adults: a 4D flow MRI study.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Comparative assessments of the COSMED adaptive mixing chamber vs. breath-by-breath methods for oxygen uptake measurements in recreationally active adults.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Can we assess exercise metabolism from skin? Metabolomic profiles in skin dialysate collected during exercise.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
See all related articles

Related Experiment Video

Updated: Jul 1, 2025

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge
09:32

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge

Published on: January 20, 2023

3.4K

Jugular venous flow dynamics during acute weightlessness.

Karina Marshall-Goebel1, Stuart M C Lee2, Jason R Lytle2

  • 1NASA Johnson Space Center, Houston, Texas, United States.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|March 14, 2024
PubMed
Summary
This summary is machine-generated.

Spaceflight causes fluid shifts, leading to internal jugular vein (IJV) distension. Acute weightlessness further increases IJV size and can cause flow stasis in the left IJV, potentially increasing thrombosis risk.

Keywords:
fluid shiftsinternal jugular veinparabolic flightspaceflight analog

More Related Videos

Coherence between Brain Cortical Function and Neurocognitive Performance during Changed Gravity Conditions
12:29

Coherence between Brain Cortical Function and Neurocognitive Performance during Changed Gravity Conditions

Published on: May 23, 2011

19.5K
Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
14:09

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Published on: March 21, 2013

20.8K

Related Experiment Videos

Last Updated: Jul 1, 2025

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge
09:32

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge

Published on: January 20, 2023

3.4K
Coherence between Brain Cortical Function and Neurocognitive Performance during Changed Gravity Conditions
12:29

Coherence between Brain Cortical Function and Neurocognitive Performance during Changed Gravity Conditions

Published on: May 23, 2011

19.5K
Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
14:09

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Published on: March 21, 2013

20.8K

Area of Science:

  • Cardiovascular Physiology
  • Space Medicine
  • Venous Hemodynamics

Background:

  • Spaceflight induces cephalad fluid shifts, altering venous hemodynamics.
  • Internal jugular vein (IJV) distension and potential thrombosis risk are concerns during space missions.

Purpose of the Study:

  • To investigate the effects of acute weightlessness (0-G) on IJV dimensions and blood flow dynamics.
  • To assess changes in IJV cross-sectional area (CSA) and flow patterns during parabolic flight.

Main Methods:

  • Two-dimensional (2-D) ultrasound measured IJV CSA.
  • Doppler ultrasound characterized venous blood flow patterns.
  • Measurements were taken in seated, supine (1-G), and supine (0-G) conditions during parabolic flight.

Main Results:

  • Supine posture increased IJV CSA on Earth (1-G).
  • Entry into 0-G further increased IJV CSA bilaterally compared to supine 1-G.
  • Flow stasis was observed in the left IJV of one participant during 0-G, persisting during level flight.

Conclusions:

  • Acute weightlessness alters cerebral outflow dynamics in the left IJV.
  • These alterations may elevate the risk of venous thrombosis during spaceflight.
  • IJV distension and potential flow stasis are significant findings for astronaut health.