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Updated: Jul 1, 2025

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Measurement of In Vitro Integration Activity of HIV-1 Preintegration Complexes
Published on: February 22, 2017
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A proposal for a simplified measure of HIV preexposure prophylaxis prevention-effective adherence in self-report
Doug Fraser1, Martin Holt2, Jason J Ong3,4
1The Kirby Institute, UNSW Sydney.
AIDS (London, England)
|March 14, 2024
Abstract:
Evaluating HIV preexposure prophylaxis (PrEP) use and HIV risk events concurrently remains challenging. We developed a single question method for measuring prevention-effective adherence with PrEP in self-report questionnaires. In a questionnaire completed by 409 gay and bisexual men, 46% reported condomless anal sex that was not covered by their own PrEP use, and this was more common among younger, lower-income participants. Refining this questionnaire item could improve measurement of prevention-effective adherence.

