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A Critical Review on the Long-Term COVID-19 Impacts on Patients With Diabetes

Sumel Ashique1, Neeraj Mishra2, Ashish Garg3

  • 1Department of Pharmaceutical Sciences, Bengal College of Pharmaceutical Sciences & Research, Durgapur, West Bengal, India.

The American Journal of Medicine
|March 14, 2024
PubMed

Insights

Individuals with diabetes face increased risks from COVID-19, including higher mortality. Research explores how SARS-CoV-2 impacts diabetic patients and potential therapeutic strategies for better outcomes.

Area of Science:

  • Endocrinology
  • Infectious Diseases
  • Public Health

Background:

  • Coronavirus disease 2019 (COVID-19) is a global health crisis.
  • Individuals with diabetes are at higher risk for severe COVID-19 outcomes.
  • This review summarizes the long-term effects of SARS-CoV-2 on diabetic patients.

Purpose of the Study:

  • To provide a practical summary of COVID-19's long-term impacts on diabetes patients.
  • To examine SARS-CoV-2 effects, mortality rates, mechanisms, and complications in diabetes.
  • To explore the role of vitamin D and zinc in managing COVID-19 in diabetes.

Main Methods:

  • Literature search conducted on PubMed, Web of Science, and Science Direct.
  • Searches were limited to English-language publications up to April 2023.

Main Results:

  • COVID-19 presents significant challenges for individuals with diabetes, potentially prolonging recovery.
  • Older adults and those with diabetes are more susceptible to COVID-19 infection.
  • High blood glucose levels may facilitate SARS-CoV-2 replication; antidiabetic drugs show therapeutic potential.

Conclusions:

  • Diabetes significantly increases morbidity and mortality risk in COVID-19 patients.
  • Global efforts are focused on developing interventions to mitigate diabetes' impact on COVID-19.
Abstract

Keywords:
Diabetes mellitusLong-term COVID-19MorbidityMortalityTreatment

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