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Underrepresented and Underserved Populations in Neurological Research.
Charles C Windon1, Ashley J Jackson1, Gloria A Aguirre1
1Department of Neurology, Memory and Aging Center, University of California, San Francisco, California.
Seminars in Neurology
|March 14, 2024
Summary
Neurological research historically excludes underserved groups, impacting health equity. This study examines inclusion gaps and proposes community-based strategies to improve participation in neurological studies.
Area of Science:
- Neurology
- Health Equity
- Clinical Research
Background:
- Historically, underserved and underrepresented populations face exclusion from neurological research.
- This exclusion limits the translation of research findings into clinical practice, particularly concerning social determinants of health.
- Systemic injustices, including structural racism, contribute to these inclusion barriers.
Purpose of the Study:
- To identify inclusivity patterns and gaps in neurological research for common neurological conditions.
- To propose best practices for enhancing the participation of underserved and underrepresented populations.
- To leverage community engagement and collaboration for more equitable research.
Main Methods:
- Analysis of inclusivity patterns and gaps across common neurological conditions.
- Review of existing strategies for increasing participation.
- Case studies of community engagement and collaboration efforts.
Main Results:
- Significant gaps in representation identified across various neurological conditions.
- Effectiveness of community-based participatory research approaches highlighted.
- Barriers at individual, investigator, and systemic levels confirmed.
Conclusions:
- Addressing historical exclusion is critical for advancing neurological health equity.
- Community engagement and tailored strategies are essential for inclusive research.
- Further research is needed to refine methodologies for equitable participation.
