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Spatial multi-omics in medicinal plants: from biosynthesis pathways to industrial applications
Chen Chen1, Xiao Zhang1, Ming Yue2
1Xi'an Botanical Garden of Shaanxi Province, Institute of Botany of Shaanxi Province, Shaanxi Engineering Research Centre for Conservation and Utilization of Botanical Resources, No. 17 Cuihua South Road, 710061 Xi'an, Shaanxi Province, China.
Trends in Plant Science
|March 14, 2024
Summary
Single-cell multi-omics advances medicinal plant research. This study explores spatial multi-omics for understanding natural product biosynthesis and biomanufacturing.
Area of Science:
- Plant Science
- Molecular Biology
- Biotechnology
Background:
- Medicinal plants are crucial sources of natural products (NPs).
- Advancements in molecular sequencing and imaging enable single-cell resolution analysis.
- Understanding NP biosynthesis pathways is key for biomanufacturing.
Purpose of the Study:
- To discuss the application of spatial multi-omics in medicinal plants.
- To evaluate biosynthesis pathways of specialized products.
- To highlight opportunities and challenges in natural product biomanufacturing.
Main Methods:
- Spatial multi-omics technologies
- Molecular sequencing
- Cellular imaging
Main Results:
- Single-cell multi-omics provides unprecedented insights into medicinal plant complexity.
- Spatial multi-omics facilitates detailed analysis of NP biosynthesis.
- Identified key pathways and potential targets for biomanufacturing.
Conclusions:
- Spatial multi-omics is transforming medicinal plant research.
- This technology offers significant potential for optimizing natural product biomanufacturing.
- Further research is needed to address current challenges.
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