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Related Concept Videos

Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

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Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
156
  1. Home
  3. Association Between Triglyceride-glucose Index And Intracranial/extracranial Atherosclerotic Stenosis: Findings From A Retrospective Study.
  1. Home
  3. Association Between Triglyceride-glucose Index And Intracranial/extracranial Atherosclerotic Stenosis: Findings From A Retrospective Study.

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Association between triglyceride-glucose index and intracranial/extracranial atherosclerotic stenosis: findings from

Yu Xie1, Kuan Cen1, Bitang Dan1

  • 1Department of Neurology, Zhongnan Hospital of Wuhan University, 169 Donghu Road, Wuhan, 430000, Hubei, China.

Cardiovascular Diabetology
|March 15, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

The triglyceride-glucose (TyG) index is linked to intracranial and extracranial atherosclerotic stenosis (ICAS/ECAS). An elevated TyG index may indicate a higher risk of developing severe arterial stenosis.

Keywords:
Extracranial atherosclerotic stenosisIntracranial atherosclerotic stenosisTriglyceride-glucose index

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Area of Science:

  • Cardiovascular Medicine
  • Metabolic Syndrome Research
  • Neurology

Background:

  • The relationship between the triglyceride-glucose (TyG) index and atherosclerotic stenosis in cerebral arteries remains unclear.
  • Investigating this association can improve risk stratification for stroke and other cardiovascular events.

Purpose of the Study:

  • To examine the association between the TyG index and the presence, distribution, and severity of intracranial atherosclerotic stenosis (ICAS) and extracranial atherosclerotic stenosis (ECAS).

Main Methods:

  • Retrospective analysis of 1129 patients who underwent digital subtraction angiography (DSA) for ICAS/ECAS evaluation.
  • Logistic regression and restricted cubic splines were used to assess the relationship between TyG index and stenosis.
  • Adjustments were made for various clinical and biochemical factors.

Main Results:

  • An elevated TyG index was significantly associated with ICAS, combined ICAS/ECAS, and stenosis in both anterior and posterior circulations.
  • Higher TyG index levels correlated with increased stenosis severity and symptomatic status.
  • These associations persisted after adjusting for confounding variables.

Conclusions:

  • The triglyceride-glucose (TyG) index is associated with the presence and severity of ICAS and ECAS.
  • The TyG index may serve as a valuable biomarker for identifying individuals at risk of significant cerebral artery stenosis.