The Relationship Between Tumor Budding and Patient's Survival in Breast Cancer
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View abstract on PubMed
Summary
This summary is machine-generated.The number of tumor buds in breast cancer is a significant predictor of patient survival. This factor correlates with tumor size, stage, metastasis, and lymph node involvement, aiding in survival rate assessment.
Area Of Science
- Oncology
- Pathology
- Cancer Research
Background
- Breast cancer remains a significant global health challenge, impacting numerous women annually.
- Identifying reliable prognostic markers is crucial for improving patient outcomes.
Purpose Of The Study
- To investigate the prognostic value of tumor bud count in breast cancer patients.
- To determine the relationship between tumor bud numbers and 5-year survival rates.
- To explore correlations between tumor buds and other clinicopathological features.
Main Methods
- Retrospective analysis of 150 female breast cancer patients.
- Evaluation of intratumoral and peritumoral bud counts on H&E stained slides.
- Comparison of bud counts with clinicopathological data including age, tumor stage, grade, size, lymph node status, and metastasis.
Main Results
- A significant association was found between tumor bud count and tumor size, stage, metastasis, and lymph node involvement.
- Tumor bud count significantly correlated with the 5-year survival rate.
- No significant association was observed between tumor bud count and patient age or tumor grade.
Conclusions
- The number of tumor buds is a significant prognostic indicator in breast cancer.
- Considering tumor bud count can aid in assessing patient survival and guiding treatment strategies.
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