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Related Experiment Video

Updated: Jun 30, 2025

qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue

qPCR Is a Sensitive and Rapid Method for Detection of Cytomegaloviral DNA in Formalin-fixed, Paraffin-embedded Biopsy Tissue

Published on: July 9, 2014

Polymerase chain reaction negative cryptococcal meningitis.

Kyle T O'Meara¹, June L Chan², Stacey Ceron²

¹Department of Pulmonary & Critical Care, Cedars-Sinai Medical Center, Los Angeles, CA, United States.

Diagnostic Microbiology and Infectious Disease

|March 16, 2024

Summary

This summary is machine-generated.

Cryptococcal meningitis can occur even with a negative BioFire FilmArray meningitis/encephalitis panel. Liberal cryptococcal antigen testing is crucial for accurate diagnosis, especially in HIV-negative individuals.

Area of Science:

Infectious Diseases
Neurology
Clinical Microbiology

Background:

Subacute headache is a common presenting symptom requiring prompt diagnosis.

Keywords:

Cryptococcal antigen Cryptococcal meningitis Cryptococcus neoformans Meningitis Molecular diagnostics Polymerase chain reaction

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Cryptococcal meningitis is a serious opportunistic infection, particularly in immunocompromised individuals.

Diagnostic panels for meningitis/encephalitis aim to rapidly identify causative pathogens.