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Microvascular Decompression: Salient Surgical Principles and Technical Nuances
Published on: July 5, 2011
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Intraoperative Brainstem Auditory Evoked Potentials and Postoperative Nausea and Vomiting After Microvascular
Kyeong-O Go1, So Young Ji2, Ji-Eyon Kwon2
1Department of Neurosurgery, Gyeongsang National University Hospital, Jinju-si, Gyengsangnam-Do, South Korea.
World Neurosurgery
|March 17, 2024
Summary
Intraoperative brainstem auditory evoked potential (IBAEP) changes, specifically a Wave V peak delay over 1.0 ms, may predict postoperative nausea and vomiting (PONV) after microvascular decompression (MVD). This finding aids in identifying patients at higher risk for PONV.
Area of Science:
- Neurosurgery
- Neurophysiology
- Anesthesiology
Background:
- Postoperative nausea and vomiting (PONV) is a common complication following microvascular decompression (MVD).
- Intraoperative brainstem auditory evoked potentials (IBAEP) are used during MVD procedures.
Purpose of the Study:
- To investigate the correlation between intraoperative brainstem auditory evoked potential (IBAEP) changes and the incidence of postoperative nausea and vomiting (PONV) after microvascular decompression (MVD).
Main Methods:
- A retrospective analysis of 373 consecutive MVD cases.
- Intraoperative brainstem auditory evoked potential (IBAEP) monitoring was routinely performed.
- Postoperative nausea and vomiting (PONV) was objectively assessed by the use of rescue antiemetics.
Main Results:
- Female sex, patient-controlled analgesia (PCA) use, and longer operation times were significantly associated with increased PONV.
- A Wave V peak delay exceeding 1.0 millisecond during IBAEP monitoring showed a significant association with the need for rescue antiemetics.
- A delay of more than 1.0 ms in Wave V peak was strongly related to requiring more than 5 doses of rescue antiemetics.
Conclusions:
- A Wave V peak delay of over 1.0 millisecond during MVD may serve as a predictive marker for PONV.
- Further neurophysiological research is needed to elucidate the underlying pathophysiology of PONV after MVD.

