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Updated: Jun 30, 2025

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
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Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients

Published on: October 15, 2017

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Correlation between trough concentration and AUC for elexacaftor, tezacaftor and ivacaftor

Steffie E M Vonk1, Josje Altenburg2, Ron A A Mathôt1

  • 1Amsterdam UMC location University of Amsterdam, Department of Hospital Pharmacy & Clinical Pharmacology, Meibergdreef 9, Amsterdam, the Netherlands.

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
|March 17, 2024
PubMed

Keywords:
Area under the curveCFTR modulatorsElexacaftor-tezacaftor-ivacaftorTherapeutic drug monitoringTrough concentration

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