Related Experiment Video
Updated: Jun 30, 2025
A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression
Published on: October 6, 2019
Living Synthelectronics: A New Era for Bioelectronics Powered by Synthetic Biology.
Jing Sun1,2, Ruofan Yang1, Qingsong Li1
1Soft Bio-interface Electronics Lab, Center of Neural Engineering, CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems, Shenzhen Institute of Artificial Intelligence and Robotics for Society, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Living synthelectronics merge biology and electronics using modified cells and viruses. This innovative approach enhances human-tissue interfacing for advanced bioelectronic applications.
Area of Science:
- Bioelectronics
- Synthetic Biology
- Materials Science
Background:
- Traditional bioelectronics face biological mismatches due to the dynamic nature of human tissues.
- Existing devices often lack the adaptive and biodynamic properties inherent in biological systems.
Purpose of the Study:
- To summarize recent advances in living synthelectronics, a new paradigm in bioelectronics.
- To explore the integration of synthetic biology with electronic components.
- To highlight the potential of using living cells and viruses in electronic devices.
Main Methods:
- Reviewing strategic approaches for designing electronic devices with living cells/viruses.
- Investigating the use of modified cells and viruses as core components.
- Examining applications as building blocks, sensing components, or power sources.
Main Results:
- Living synthelectronics offer enhanced potential for informational and substance exchange with human tissues.
- Gene-edited cells and viruses are utilized as core components in hybrid electronics.
- Novel bioelectronic devices can be created using biological entities.
Conclusions:
- Living synthelectronics represent a paradigm shift in bioelectronics.
- This field promises significant contributions to the integration of bioelectronics with human tissues.
- Future research should address the challenges in developing living synthelectronics.
