Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview Of Cell Separation And Isolation01:20

Overview Of Cell Separation And Isolation

5.7K
Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
5.7K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Automated Proofreading of Digitally Reconstructed Neural Morphology Enhances Accuracy, Scalability, and Standardization.

bioRxiv : the preprint server for biology·2026
Same author

Visualization and simulation of full-scale point-neuron circuits via the Neural Circuit Visualizer web platform.

Scientific reports·2026
Same author

Hippocampome.org, a resource for subicular neuron types and beyond.

bioRxiv : the preprint server for biology·2026
Same author

Dendritome mapping reveals the spatial organization of striatal neuron morphology.

Nature neuroscience·2025
Same author

Organization and Community Usage of a Neuron Type Circuitry Knowledge Base of the Hippocampal Formation.

Biomedicines·2025
Same author

Biologically-informed excitatory and inhibitory ratio for robust spiking neural network training.

Scientific reports·2025
Same journal

MetaboNet-Bench: A Multi-modal Benchmark for Glucose Forecasting in Type 1 Diabetes.

ArXiv·2026
Same journal

A Positron Range Correction with Texture Preservation Framework in PET Imaging.

ArXiv·2026
Same journal

Automated optimization of force field parameters against ensemble-averaged measurements with Bayesian Inference of Conformational Populations.

ArXiv·2026
Same journal

Droplet Fusion as a Relaxation Process: Comparison with Shape Recovery of Newtonian and Viscoelastic Droplets.

ArXiv·2026
Same journal

Ridge-filter crosstalk in conformal proton FLASH planning: dependence on beamlet pitch and iterative mitigation.

ArXiv·2026
Same journal

Electrochemical DNA Hairpin Sensors for Differentiating Small Molecule Intercalation from Minor Groove Binding.

ArXiv·2026
See all related articles

Related Experiment Video

Updated: Jun 30, 2025

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array
07:19

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Published on: September 7, 2018

8.5K

A Novel Method for Clustering Cellular Data to Improve Classification.

Diek W Wheeler1, Giorgio A Ascoli1

  • 1Center for Neural Informatics, Structures, & Plasticity, Krasnow Institute for Advanced Study; and Bioengineering Department, Volgenau School of Engineering; George Mason University, Fairfax, VA 22030-4444, USA.

Arxiv
|March 18, 2024
PubMed
Summary
This summary is machine-generated.

This study introduces a new protocol for classifying large cellular datasets using hierarchical clustering and statistical testing. It provides an objective method to determine optimal data granularity for fields like neuroscience.

More Related Videos

Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations
12:27

Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations

Published on: February 15, 2017

7.0K
Discrimination and Characterization of Heterocellular Populations Using Quantitative Imaging Techniques
09:48

Discrimination and Characterization of Heterocellular Populations Using Quantitative Imaging Techniques

Published on: June 30, 2017

7.5K

Related Experiment Videos

Last Updated: Jun 30, 2025

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array
07:19

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Published on: September 7, 2018

8.5K
Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations
12:27

Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations

Published on: February 15, 2017

7.0K
Discrimination and Characterization of Heterocellular Populations Using Quantitative Imaging Techniques
09:48

Discrimination and Characterization of Heterocellular Populations Using Quantitative Imaging Techniques

Published on: June 30, 2017

7.5K

Area of Science:

  • Neuroscience and computational biology
  • Data science and machine learning

Background:

  • The rapid growth of cellular data in fields like neuroscience necessitates efficient organization and interpretation methods.
  • Hierarchical clustering is a common technique for partitioning large datasets, but lacks objective criteria for determining classification granularity.

Conclusions:

  • The protocol provides an objective and systematic approach to classifying large cellular datasets.
  • This method enhances the interpretation of complex biological data, particularly in neuroscience.
  • The general applicability across various data types makes it a valuable tool for data analysis.