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Updated: Jun 30, 2025

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
Published on: December 15, 2023
Dynamically stabilized recurrent neural network optimized with Artificial Gorilla Troops espoused Alzheimer's
G Sudha1, N Saravanan2, M Muthalakshmi3
1Department of Biomedical Engineering, Muthayammal Engineering College, Rasipuram, Namakkal, Tamil Nadu India.
This study introduces a new computer-aided diagnosis system for Alzheimer's disease (AD) using EEG signals. The developed DSRNN-AGTO-ADD model enhances early AD detection, improving diagnostic accuracy and reducing computational time.
Area of Science:
- Biomedical Engineering
- Computational Neuroscience
- Artificial Intelligence in Medicine
Background:
- Alzheimer's disease (AD) is a progressive neurological disorder impacting cognition, necessitating early detection for effective symptom management.
- The increasing demand for healthcare services highlights the need for automated diagnostic tools to assist clinicians and improve diagnostic efficiency.
- Electroencephalogram (EEG) signals offer a non-invasive method for brain activity monitoring, holding potential for early AD identification.
Purpose of the Study:
- To develop an automated computer diagnostic scheme for identifying Alzheimer's disease (AD) using Electroencephalogram (EEG) signals.
- To propose a novel deep learning model, Dynamically Stabilized Recurrent Neural Network Optimized with Artificial Gorilla Troops (DSRNN-AGTO-ADD), for enhanced AD detection.
- To evaluate the efficacy of the proposed model in improving diagnostic accuracy and reducing computational load compared to existing methods.
Main Methods:
- Preprocessing EEG signals using a Dynamic Context-Sensitive Filter (DCSF) to remove noise and interference.
- Feature extraction using Adaptive and Concise Empirical Wavelet Transform (ACEWT), incorporating signal characteristics like power, variance, and kurtosis.
- Classification of extracted features using a Dynamically Stabilized Recurrent Neural Network (DSRNN), optimized with the Artificial Gorilla Troops Optimization Algorithm (AGTOA).
Main Results:
- The DSRNN-AGTO-ADD approach demonstrated significant improvements in diagnostic performance.
- Achieved higher specificity (12.98%, 5.98%, 23.45%) and Receiver Operating Characteristic (ROC) scores (29.29%, 8.365%, 8.551%, 7.915%) compared to existing methods.
- Showcased reduced computation time (29.98%, 23.32%, 19.76%), indicating computational efficiency.
Conclusions:
- The proposed DSRNN-AGTO-ADD algorithm presents a promising automated tool for accurate and efficient Alzheimer's disease diagnosis from EEG signals.
- The integration of advanced signal processing and optimization techniques enhances the diagnostic capabilities for neurological disorders.
- This research contributes to the development of AI-driven healthcare solutions for early disease detection and management.
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