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Published on: June 11, 2012
Quality of Life and Glucose Regulation in Pediatric Patients with Type 1 Diabetes: A Study in the Ningxia Hui
1Department of Pediatrics, General Hospital of Ningxia Medical University, Yinchuan, 750004, People's Republic of China.
Insights
Pediatric patients with type 1 diabetes in Ningxia have poor glucose control and quality of life. Enhancing glucose regulation through diet, monitoring, and education is crucial for improving outcomes.
Area of Science:
- Pediatrics
- Endocrinology
- Public Health
Background:
- Type 1 diabetes (T1DM) significantly impacts children's quality of life (QOL).
- Effective glycemic control is essential for managing T1DM and preventing complications.
- Understanding regional disparities in T1DM management is vital for targeted interventions.
Purpose of the Study:
- To assess the quality of life (QOL) in pediatric patients with type 1 diabetes (T1DM).
- To evaluate the current status of plasma glucose regulation in children with T1DM in the Ningxia Hui autonomous region.
- To identify factors influencing QOL and glycemic control in this population.
Main Methods:
- A cohort of 136 pediatric patients with T1DM was studied.
- Data collected included general information, QOL questionnaires, and HbA1c levels.
- Factors affecting glucose control and QOL were investigated.
Main Results:
- Mean HbA1c was 8.7%, with 43.3% of patients showing poor glycemic control.
- Disease duration, age, glucose monitoring frequency, CGM use, DKA, and maternal education influenced glucose control.
- Poor glycemic control, DKA, and inadequate health education negatively impacted QOL.
Conclusions:
- Glycemic regulation in pediatric T1DM patients in Ningxia is suboptimal, affecting QOL.
- Comprehensive strategies including dietary management, rigorous glucose monitoring, and enhanced health education are needed.
- Improving glucose control is key to enhancing QOL for children with T1DM.
Objective:
In this study, we aimed to evaluate the current status of the quality of life (QOL) of pediatric patients and plasma glucose concentration regulation in children with type 1 diabetes (T1DM) in the Ningxia Hui autonomous region.
Methods:
The study involved children with T1DM admitted to the General Hospital of Ningxia Medical University between October 2011 and October 2021. The children and their parents completed general information and quality of life (QOL) questionnaires. The regulation of plasma glucose concentration was assessed based on HbA1c levels, and plasma glucose and QOL-influencing components were investigated.
Results:
Among the 136 pediatric patients diagnosed with T1DM, the mean glycated hemoglobin (HbA1c) level was recorded at 8.7% (7.2%, 10.5%). A breakdown of the patient cohort revealed that 44 patients (32.4%) demonstrated good regulation of plasma glucose, 33 patients (24.3%) exhibited acceptable glycemic control, and 59 patients (43.3%) displayed poor regulation of plasma glucose. The control of plasma glucose in pediatric patients diagnosed with T1DM was affected by the duration of the disease, the patient's age, the frequency of daily plasma glucose measurements, the use of CGM, diabetic ketoacidosis (DKA), and the education level of the mother. The control of plasma glucose, dietary management, DKA, the ability to learn, and health education are interfering factors of quality of life in children diagnosed with T1DM. Effective control of plasma glucose may ensure the QOL in children with T1DM, and DKA was the risk factor for QOL.
Conclusion:
In Ningxia, the regulation of plasma glucose in pediatric and adolescent patients with T1DM remains suboptimal, leading to poor QOL. There is a pressing need to enhance glucose regulation and QOL through comprehensive strategies, which include reinforced dietary management, rigorous monitoring of plasma glucose levels, and heightened health education levels.
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