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Published on: July 5, 2021
A Case of Pan-TRK Positive Dermatofibrosarcoma Protuberans Located on the Nose
Romane Teshima1, Taiyo Hitaka1, Hitomi Sugino1
1Dermatology, University of Occupational and Environmental Health, Kitakyushu, JPN.
Abstract:
Dermatofibrosarcoma protuberans (DFSP) is a rare and infiltrative soft tissue tumor. Our report details a distinctive case of DFSP with pan-TRK positivity in the right nasal dorsum of a 46-year-old female. Histological analysis identified NTRK fusion gene involvement in this patient, detectable through pan-TRK immunostaining. The case underscores the significance of comprehensive management for pan-TRK-positive DFSP in challenging facial locations, indicating the potential efficacy of TRK inhibitors.

