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Updated: May 6, 2026

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Published on: August 18, 2015
Pediatric Cerebral Venous Sinus Thrombosis: A Case Report
Pruthvi Patel1, Shirley M Gandhi2, Philip P Breton3
1Internal Medicine, Alabama College of Osteopathic Medicine, Dothan, USA.
Insights
Cerebral venous sinus thrombosis (CVST) in infants, a rare condition, can cause serious complications due to delayed diagnosis. This case highlights a neonate diagnosed with CVST presenting with nonspecific symptoms like lethargy and vomiting.
Area of Science:
- Pediatric Neurology
- Vascular Neurology
- Neonatal Medicine
Background:
- Cerebral venous sinus thrombosis (CVST) in infants is uncommon and often presents with vague symptoms, delaying diagnosis and treatment.
- Impaired cerebral venous drainage due to thrombus formation can lead to severe neurological complications.
Abstract:
Cerebral venous sinus thrombosis (CVST) in infants is a rare vascular disorder that presents with nonspecific symptoms leading to a delay in diagnosis and treatment. Thrombus formation in the cerebral sinuses prevents blood from draining out of the brain leading to local and systemic complications. Here, we present an 11-week-old patient who presented to the emergency department (ED) with three days of lethargy, multiple episodes of projectile emesis, increased fussiness, and downward gaze. A CT scan demonstrated intraventricular hemorrhage (IVH) with acute hydrocephalus. A CT venogram of the cranial vault with contrast showed a large intraluminal thrombus occupying the right transverse sinus and torcula with proximal extension into the left transverse sinus confirming the diagnosis of CVST.
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