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Updated: May 12, 2026

Cone Beam Intraoperative Computed Tomography-based Image Guidance for Minimally Invasive Transforaminal Interbody Fusion
Published on: August 6, 2019
Radiological and Clinical Outcomes of Transforaminal vs. Posterior Lumbar Interbody Fusions: A Systematic Review
Payman Vahedi1, Marjan Gholghasemi, George Rymarczuk
1Islamic Azad University, Tehran Medical Sciences, Farhikhtegan Hospital, Department of Neurosurgery, Tehran, Iran.
Transforaminal lumbar interbody fusion (TLIF) shows better outcomes than posterior lumbar interbody fusion (PLIF), with fewer neurological deficits, less blood loss, and shorter operation times. Further research is recommended to confirm TLIF
Area of Science:
- Spine surgery
- Minimally invasive spine surgery
- Lumbar fusion techniques
Background:
- Posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) are common surgical techniques for lumbar spinal fusion.
- Comparing the outcomes of these two techniques is crucial for optimizing patient care.
Approach:
- A systematic review and meta-analysis was conducted by querying major online databases for comparative studies.
- Studies published between January 2000 and August 2021 were included, focusing on fusion outcomes, complications, and operative parameters.
Key Points:
- TLIF demonstrated a significantly lower rate of neurological deficits (10% vs. 24%) compared to PLIF.
- PLIF procedures had longer mean operation times (178.5 min vs. 160 min) and greater estimated blood loss (515 ml vs. 405 ml).
- No significant differences were observed in fusion rates, length of hospital stay, or surgical site infections between the two techniques.
Conclusions:
- TLIF appears to offer advantages over PLIF, including reduced neurological complications, decreased blood loss, and shorter operative times.
- Factors like surgeon experience and instrumentation may influence specific complication rates such as cage migration or pseudoarthrosis.
- Multicenter prospective trials are warranted to definitively establish the superiority of TLIF over PLIF.
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