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Cost-effectiveness of point-of-care diagnostics for AMR: a systematic review
Abraham Tolley1, Akhil Bansal2,3, Rebecca Murerwa4
1School of Clinical Medicine, University of Cambridge, Cambridge, UK.
The Journal of Antimicrobial Chemotherapy
|March 18, 2024
Summary
Point-of-care tests (POCTs) can be cost-effective in reducing antimicrobial prescribing and the burden of antimicrobial resistance (AMR). Some POCTs demonstrate clinical benefits, warranting further large-scale evaluation.
Area of Science:
- Health Economics
- Infectious Disease Management
- Diagnostic Technologies
Background:
- Antimicrobial resistance (AMR) poses a significant global health threat, projected to cause 10 million deaths and cost $100 trillion annually by 2050.
- Point-of-care tests (POCTs) offer a potential cost-effective strategy to mitigate the impact of AMR.
Conclusions:
- Evidence supports the cost-effectiveness of certain POCTs in reducing antimicrobial prescribing, often with concurrent clinical benefits.
- C-reactive protein (CRP) POCTs, in both high- and low-income settings, show particular promise.
- Further large-scale clinical evaluation of these cost-effective POCT interventions is recommended.
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