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Updated: Jun 30, 2025

Surgical Models of Gastroesophageal Reflux with Mice
Published on: August 25, 2015
Anti-reflux mucosectomy (ARMS) for refractory gastroesophageal reflux disease
1Department of Gastroenterology, Ningbo Medical Center Lihuili Hospital, 1111 Jiangnan Road, Ningbo, 315000, China.
Abstract:
Gastroesophageal reflux disease (GERD) is one of the most common diseases seen by gastroenterologists worldwide. A significant proportion of patients have a suboptimal response to acid inhibitors, especially proton pump inhibitors and potassium-competitive acid blockers. Due to concerns regarding the safety of long-term medication, many patients are unwilling to take lifelong medication. Endoscopic antireflux management offers a minimally invasive option for GERD patients. In recent decades, there have been several endoscopic antireflux therapies, including radiofrequency therapy, transoral fundoplication, and mucosal resection or mucosal ablation. Of these, antireflux mucosectomy (ARMS) is an effective and safe therapy for refractory GERD. This review provides an updated summary of antireflux mucosectomy.
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