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Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
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Pulmonary Spindle Cell Carcinoma: As Rare as a Hen's Teeth
Rudra P Samanta1, Srikant Agarwal1, Ruchi Agrawal2
1Department of Pulmonology, Tata Main Hospital, Jamshedpur, IND.
Cureus
|March 19, 2024
Summary
A rare spindle cell carcinoma (SpCC) was diagnosed in a 70-year-old man presenting with pneumonia-like symptoms. This aggressive non-small cell lung cancer subtype has a poor prognosis and limited research data.
Area of Science:
- Oncology
- Pulmonology
- Pathology
Background:
- A 70-year-old male presented with symptoms suggestive of infectious lung disease, including pneumonia and tuberculosis.
- Initial investigations revealed a lung mass on chest X-ray and CT scan.
Observation:
- The lung mass was biopsied for histopathological examination and immunohistochemical staining.
- The biopsy confirmed the presence of spindle cell carcinoma (SpCC).
Findings:
- Immunohistochemistry showed vimentin and cytokeratin positivity, characteristic of SpCC.
- Spindle cell carcinoma is a rare subtype of non-small cell lung carcinoma (NSCLC).
Implications:
- Spindle cell lung cancer is associated with a poor prognosis.
- The rarity of SpCC necessitates further research into its epidemiology and survival outcomes.
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