A highly sensitive ratiometric fluorescence immunoassay based on bioorthogonal nanozymes
Xiajian Liu1, Nianhua Wang2, Yixuan Hou1
1School of Biomedical Sciences and Engineering, Guangzhou International Campus, South China University of Technology, Guangzhou, 511442, P. R. China. yuanyy@scut.edu.cn.
Abstract:
We designed a novel ratiometric fluorescence immunoassay based on bioorthogonal nanozymes for carcinoembryonic antigen detection. The analytical performance of our designed immunoassay showed a wide linear range, a low detection limit, good reproducibility, selectivity and stability. Thus, bioorthogonal nanozymes hold great potential applications in clinical diagnoses.
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