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Updated: Jun 30, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Generation and Radical-Radical Cross-Coupling of Alkenyloxy Radical
Yunquan Man1, Bo Xu1
1Key Laboratory of Science and Technology of Eco-Textiles, Ministry of Education, College of Chemistry and Chemical Engineering, Donghua University, Shanghai 201620, China.
Abstract:
Alkene-attached oxygen radicals are rarely used, as highly reactive oxygen radicals are incompatible with the alkene moiety. The direct radical-radical cross-coupling of O radicals is also challenging (limited to N-O bond formation) because of the lack of suitable persistent radical species. This study demonstrated the feasibility of using Breslow intermediate radical (BIR) as a persistent radical to capture unstable π-conjugated O radicals and allow the C-O radical-radical cross-coupling.
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