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Related Experiment Video

Updated: Jun 30, 2025

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Key Performance Indicators and Metrics for the Implementation of an Oral Chemotherapy Adherence Program.

Benyam Muluneh1,2, James B Collins1,3, Brian Lam1

  • 11UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC.

Journal of the National Comprehensive Cancer Network : JNCCN
|March 19, 2024
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Summary

This study identified 11 key performance indicators (KPIs) to measure the success of oral anticancer agent (OAA) adherence programs. These KPIs will help improve patient care and program implementation in cancer centers.

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Area of Science:

  • Oncology Pharmacy
  • Health Services Research
  • Patient Adherence

Background:

  • Oral anticancer agents (OAAs) have transformed cancer care, but their effectiveness relies on patient adherence.
  • Pharmacy-driven models exist to improve adherence, yet lack measurable key performance indicators (KPIs) for adoption.
  • This study aimed to identify specific KPIs, metrics, and targets for evaluating OAA adherence programs.

Approach:

  • Conducted a literature review to identify initial KPIs, metrics, and targets.
  • Assembled an advisory panel of clinicians, administrators, and patients for consensus.
  • Utilized a Qualtrics survey and consensus discussion to validate KPIs for a structured adherence intervention.

Key Points:

  • Identified 11 KPIs: time to initiation, adherence rate, adverse events, financial toxicity, patient satisfaction, ED visits, hospital admissions, barrier assessment, social work referrals, time in care phases, and revenue.
  • KPIs cover clinical, financial, and patient-reported outcomes.
  • These KPIs provide a framework for measuring the impact of OAA adherence programs.

Conclusions:

  • Successfully identified 11 measurable KPIs for evaluating oral anticancer agent adherence programs.
  • These KPIs will be piloted in academic and community cancer centers to assess program effectiveness.
  • Implementation of these KPIs is expected to enhance patient care and program sustainability.