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SPREAD: Spatiotemporal Pathogen Relationships and Epidemiological Analysis Dashboard.

Andrea De Ruvo1,2, Alessandro De Luca3, Andrea Bucciacchio3

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The Spatiotemporal Phylogenomic Research and Epidemiological Analysis Dashboard (SPREAD) enhances infectious disease surveillance by integrating genomic, geographic, and temporal data. This web-based tool aids public health officials in rapidly identifying disease transmission clusters for timely interventions.

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Area of Science:

  • Public Health
  • Epidemiology
  • Genomics

Background:

  • Effective infectious disease outbreak control requires integrating genetic, geographical, and temporal data.
  • Traditional surveillance methods often struggle to combine these crucial data types for comprehensive transmission analysis.

Purpose of the Study:

  • To introduce the Spatiotemporal Phylogenomic Research and Epidemiological Analysis Dashboard (SPREAD) as a novel web-based application for enhanced disease surveillance.
  • To demonstrate SPREAD's capability in integrating diverse data for understanding disease spread and facilitating public health responses.

Main Methods:

  • SPREAD integrates modules for genomic relationship analysis, pathogen identification, and spatial mapping.
  • The application supports both bacteria (allele calling) and viruses (variant calling).
  • SPREAD is a standalone, web-based application designed for accessibility without requiring extensive IT infrastructure.

Main Results:

  • SPREAD facilitates detailed views of disease transmission across populations and territories.
  • Initial deployments have successfully identified transmission clusters, enabling prompt public health interventions.
  • The dashboard provides intuitive navigation of complex datasets for advanced surveillance.

Conclusions:

  • SPREAD offers a promising digital health innovation for infectious disease surveillance.
  • Its integrated approach and user-centered design empower public health contexts with advanced capabilities.
  • The tool significantly aids in the rapid identification and control of infectious disease outbreaks.