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Interdevice Agreement between a Smartphone and a Commercial Pupillometer
Yamini Rattan1, Kawalinder Kaur Girgla1, Gaurav Mahajan2
1Department of Physiology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India.
International Journal of Applied & Basic Medical Research
|March 20, 2024
Summary
Smartphone pupillometry measurements show poor agreement with commercial devices, indicating unreliability for clinical use in the Indian population. Further research and software improvements are needed for smartphone pupillometry validation.
Area of Science:
- Ophthalmology
- Medical Devices
- Clinical Diagnostics
Background:
- Pupillometry device reliability varies, hindering standardization of dynamic pupillometry parameters.
- Evaluating agreement between different pupillometer devices is crucial for clinical utility.
- Further studies are needed to assess pupillometer agreement and clinical applicability.
Purpose of the Study:
- To evaluate the agreement between smartphone and commercial pupillometer measurements.
- To assess the utility of smartphone pupillometry in routine clinical settings.
Main Methods:
- A single investigator measured pupils of 100 healthy participants (200 eyes) using both a smartphone application and a commercial pupillometer.
- Pupillary measurements included maximum diameter, minimum diameter, latency, constriction velocity (CV), and dilatation velocity.
- Intraclass correlation coefficient (ICC) was used to assess agreement.
Main Results:
- Statistically significant differences were observed between smartphone and commercial pupillometers for most parameters (P < 0.05), except latency (P = 0.36).
- Poor agreement (ICC < 0.50) was found between the smartphone application and the commercial pupillometer.
- Smartphone pupillometry measurements were deemed unreliable.
Conclusions:
- Smartphone pupillometry applications are currently unreliable and not ideal substitutes for commercial pupillometers in the Indian population.
- Further research with larger sample sizes and improved software processing is required.
- The clinical utility of smartphone pupillometry needs further investigation.

