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Updated: Jun 30, 2025
28:13
Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
33.4K
The Intersection of Atrial Fibrillation and Coronary Artery Disease in Middle Eastern Patients. Analysis from the
Ayman Hammoudeh1, Yahya Badaineh1, Ramzi Tabbalat2
1Department of Cardiology, Istishari Hospital, 44 Kindi Street, Amman 11954, Jordan.
Global Heart
|March 20, 2024
Summary
In Middle Eastern patients with atrial fibrillation (AF), coronary artery disease (CAD) affects 10.7% and is linked to poorer health and worse one-year outcomes. This highlights the importance of managing both conditions together.
Area of Science:
- Cardiology
- Internal Medicine
- Epidemiology
Background:
- Limited clinical research exists on the association between atrial fibrillation (AF) and coronary artery disease (CAD) in the Middle East.
- Understanding this comorbidity is crucial for managing cardiovascular health in the region.
Purpose of the Study:
- To assess the impact of CAD on the clinical characteristics of Middle Eastern patients with AF.
- To evaluate the one-year outcomes for AF patients with and without concomitant CAD.
Main Methods:
- The Jordan AF Study enrolled 2020 AF patients from May 2019 to December 2020 across 29 centers.
- Compared clinical profiles, medication use, and one-year outcomes between AF patients with CAD (AF/CAD) and those without (AF/no CAD).
Main Results:
- 10.7% of AF patients had CAD. AF/CAD patients exhibited higher rates of hypertension, diabetes, heart failure, and chronic kidney disease.
- AF/CAD patients had higher CHA₂DS₂-VASc and HAS-BLED scores, lower ejection fraction, and larger left atrial size.
- One-year outcomes showed higher hospitalization rates, acute coronary syndrome, revascularization, and all-cause mortality in the AF/CAD group.
Conclusions:
- The coexistence of AF and CAD in Middle Eastern patients is associated with a more complex clinical profile.
- Patients with both AF and CAD experienced significantly worse one-year outcomes, including increased mortality.
- This study underscores the need for integrated management strategies for AF and CAD in this population.
Keywords:
Atrial fibrillationCoronary artery diseaseMiddle Eastern populationOral anticoagulant agentsPrognosisMore Related Videos
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