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Updated: Jun 30, 2025

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
Published on: May 26, 2019
Isolable Geminal Bisgermenolates: A New Synthon in Organometallic Chemistry
Manfred Drusgala1, Philipp Frühwirt2, Gabriel Glotz2
1Institute of Inorganic Chemistry Graz University of Technology Stremayrgasse 9/IV 8010 Graz Austria.
Abstract:
We have synthesized the first isolable geminal bisenolates L2K2Ge[(CO)R]2 (R=2,4,6-trimethylphenyl (2 a,b), L=THF for (2 a) or [18]-crown-6 for (2 b)), a new synthon for the synthesis of organometallic reagents. The formation of these derivatives was confirmed by NMR spectroscopy and X-ray crystallographic analysis. The UV/Vis spectra of these anions show three distinct bands, which were assigned by DFT calculations. The efficiency of 2 a,b to serve as new building block in macromolecular chemistry is demonstrated by the reactions with two different types of electrophiles (acid chlorides and alkyl halides). In all cases the salt metathesis reaction gave rise to novel Ge-based photoinitiators in good yields.
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