Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measuring Local Exothermic Effects During the Oxidative Coupling of Methane Using Operando Luminescence Thermometry.

Angewandte Chemie (International ed. in English)·2026
Same author

Enhanced Formation of Dicarboxylic Acids in the Catalytic Oxidation of Polyethylene With O<sub>2</sub> and NO<sub>x</sub>.

Angewandte Chemie (International ed. in English)·2026
Same author

Mechanism of O<sub>2</sub>/NO-Promoted Oxidative C-C Bond Cleavage in Linear Alkanes.

Journal of the American Chemical Society·2026
Same author

Towards <i>stimulando</i> time-resolved infrared spectroscopy to study intermittent light-stimulated CO<sub>2</sub> hydrogenation.

Faraday discussions·2026
Same author

Grand Challenges and Opportunities in Stimulated Dynamic and Resonant Catalysis.

ACS catalysis·2026
Same author

Influence of cations on nitrate-to-ammonia synthesis over NiO:SnO<sub>2</sub>: insights from differential electrochemical mass spectrometry.

Chemical communications (Cambridge, England)·2026
Same journal

Lasing characteristics and stress-tuning effects in GaN beam microcavities.

Nanoscale·2026
Same journal

Unraveling the synergy of core doping and the motif shell in atomically precise PtAg nanoclusters for CF<sub>3</sub>-ketone alkynylation.

Nanoscale·2026
Same journal

A dual-functional heavy-metal-free quantum dot/TiO<sub>2</sub> hybrid system for simultaneous pollutant degradation and green hydrogen production.

Nanoscale·2026
Same journal

Rational design of spherical NiCoB@rGO nanocomposites for efficient electrochemical energy storage.

Nanoscale·2026
Same journal

Ligand-controlled engineering of Cu-H active sites on Cu<sub>25</sub> hydride nanoclusters for efficient CO<sub>2</sub> electroreduction.

Nanoscale·2026
Same journal

Isostructural Co/Ni-containing banana-shaped polyoxometalates for visible-light-driven hydrogen production.

Nanoscale·2026
See all related articles

Related Experiment Video

Updated: Jun 30, 2025

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.3K

Alternative nano-lithographic tools for shell-isolated nanoparticle enhanced Raman spectroscopy substrates.

Ketki Srivastava1, Thimo S Jacobs2, Stefan Ostendorp3

  • 1BIOS Lab on Chip Group, Mesa+ Institute of Nanotechnology, University of Twente, The Netherlands. m.odijk@utwente.nl.

Nanoscale
|March 20, 2024
PubMed
Summary
This summary is machine-generated.

This study introduces atomic layer deposition (ALD) to create pin-hole-free shells for shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS) substrates. This method enables reliable chemical sensing with enhanced Raman signals from lithographically fabricated nanostructures.

More Related Videos

Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids
06:15

Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids

Published on: June 16, 2023

1.9K
Author Spotlight: Tracking Electrochemistry on Single Nanoparticles with Surface-Enhanced Raman Scattering Spectroscopy and Microscopy
10:59

Author Spotlight: Tracking Electrochemistry on Single Nanoparticles with Surface-Enhanced Raman Scattering Spectroscopy and Microscopy

Published on: May 12, 2023

2.5K

Related Experiment Videos

Last Updated: Jun 30, 2025

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.3K
Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids
06:15

Author Spotlight: Advancements and Applications in Nanoparticle Synthesis Through Laser Ablation in Liquids

Published on: June 16, 2023

1.9K
Author Spotlight: Tracking Electrochemistry on Single Nanoparticles with Surface-Enhanced Raman Scattering Spectroscopy and Microscopy
10:59

Author Spotlight: Tracking Electrochemistry on Single Nanoparticles with Surface-Enhanced Raman Scattering Spectroscopy and Microscopy

Published on: May 12, 2023

2.5K

Area of Science:

  • Nanotechnology
  • Surface Science
  • Spectroscopy

Background:

  • Metal nanoparticles (MNPs) are used as surface-enhanced Raman spectroscopy (SERS) substrates for reaction monitoring.
  • Catalytically active MNPs can cause interference from side products.
  • Shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS) uses insulating shells to prevent MNP catalysis, but achieving pin-hole-free shells with high enhancement is challenging.

Purpose of the Study:

  • To explore alternative methods for fabricating shell-isolated plasmonic nanostructures for chemical sensing.
  • To investigate combinations of chemical synthesis and lithographic techniques for SHINERS substrates.
  • To evaluate the effectiveness of atomic layer deposition (ALD) for creating robust, pin-hole-free shells.

Main Methods:

  • Comparison of three fabrication approaches: chemically synthesized MNPs with chemical shells, lithographic substrates with chemical shells, and lithographic substrates with ALD shells.
  • Utilizing atomic layer deposition (ALD) for shell fabrication.
  • Characterization of enhancement factors and verification of shell integrity using a gold etchant.

Main Results:

  • Atomic layer deposition (ALD) enables the fabrication of controllable and reproducible pin-hole-free shells.
  • Lithographic SHINER substrates coated with a 2.8 nm aluminum oxide shell achieved an enhancement factor of 7.5 × 10³ ± 17%.
  • ALD-fabricated shells were confirmed to be pin-hole-free through etching experiments.

Conclusions:

  • ALD is a superior method for creating pin-hole-free shells for SHINERS applications.
  • Lithographically fabricated SHINER substrates offer a promising route for sensitive and selective chemical sensing.
  • This work overcomes limitations in traditional SHINERS fabrication, enabling wider applications in catalysis and chemical analysis.