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Updated: Jun 30, 2025

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The Use of 5-Hydroxymethylfurfural (5-HMF) in Multi-Component Hantzsch Dihydropyridine Synthesis

Jingjing Jiang1, Yves Queneau1, Florence Popowycz1

  • 1INSA Lyon, Université Lyon 1, CNRS, CPE, UMR 5246, ICBMS, 1 rue Victor Grignard, F-69621, Villeurbanne Cedex.

Chemsuschem
|March 20, 2024
PubMed
Summary

This study explores using 5-hydroxymethylfurfural (5-HMF) in Hantzsch dihydropyridine synthesis via multi-component reactions. It efficiently produces symmetrical and unsymmetrical dihydropyridines from renewable 5-HMF.

Keywords:
1,4-dihydropyridines5-HMFHantzschMCRammonium acetatesolvent-free

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