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Post Trauma Acinetobacter Baumanii Meningitis Treatment Approach.
Cem Erdoğan1, Zeynep Betul Balcioglu2, Isa Seida2
1Departmant of Anesthesiology and Reanimation, Istanbul Medipol University, Istanbul, Turkey.
Acinetobacter baumannii meningitis, a severe nosocomial infection, can be successfully treated with intrathecal colistin and polymyxin B. This approach improves survival outcomes for drug-resistant infections, even when antibiotics struggle to cross the blood-brain barrier.
Area of Science:
- Infectious Diseases
- Neurosurgery
- Pharmacology
Background:
- Acinetobacter baumannii is a significant cause of nosocomial infections, particularly following surgery or trauma.
- A. baumannii meningitis, often complicated by ventriculitis and abscesses, poses a substantial mortality risk.
- Multi-drug resistance in A. baumannii complicates treatment strategies.
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