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Updated: Jul 31, 2026

A Small Animal Model of Ex Vivo Normothermic Liver Perfusion
Published on: June 27, 2018
Abdominal normothermic regional perfusion in the United States: current state and future directions
Anji Wall1, Amar Gupta, Giuliano Testa
1Baylor University Medical Center.
Purpose Of Review:
Normothermic regional perfusion (NRP) is a novel procurement technique for donation after circulatory death (DCD) in the United States. It was pioneered by cardiothoracic surgery programs and is now being applied to abdominal-only organ donors by abdominal transplant programs.
Recent Findings:
Liver and kidney transplantation from thoracoabdominal NRP (TA-NRP) donors in the United States was found to have lower rates of delayed kidney graft function and similar graft and patient survival versus recipients of cardiac super rapid recovery (SRR) DCD donors. The excellent outcomes with NRP have prompted the expansion of NRP technology to abdominal transplant programs.
Summary:
Excellent early outcomes with liver and kidney transplantation have prompted the growth of NC-NRP procurement for abdominal-only DCD donors across the US, and now requires standardization of technical and nontechnical aspects of this procedure.
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