Related Experiment Video
Updated: Jun 30, 2025
06:39
Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
15.7K
[Provocation tests]
Lucila Camargo López de Oliveira1, Beni Morgenstern2
1Doctora en Ciencias, Profesora adjunta de la Disciplina de Alergia e Inmunología, Departamento de Pediatría da UNIFESP, Brasil.todoasma@gmail.com.
Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|March 20, 2024
Summary
Oral food challenges are the gold standard for diagnosing food allergies, outperforming blood and skin tests. They help assess tolerance and manage allergy risks in uncertain cases.
Area of Science:
- Clinical immunology
- Allergology
- Diagnostic procedures
Context:
- Food allergies are a growing public health concern.
- Accurate diagnosis is crucial for effective management.
- Existing tests like IgE serum and prick tests indicate sensitization but not definitive allergy.
Purpose:
- To highlight the diagnostic superiority of oral provocation tests (OPTs) for food allergies.
- To outline the indications for performing OPTs.
- To describe the different types of OPTs and their applications.
Summary:
- Oral provocation tests (OPTs) involve supervised, incremental food administration to diagnose allergies.
- OPTs are considered superior to specific IgE serum or prick tests for definitive diagnosis.
- Indications include diagnostic uncertainty, tolerance assessment, and cross-reactivity evaluation.
- Types include open, single-blind, and double-blind placebo-controlled tests, with open tests often preferred for young children.
Impact:
- Improved accuracy in food allergy diagnosis.
- Better patient management through definitive allergy identification.
- Enhanced understanding of tolerance and cross-reactivity.
- Guidance on selecting appropriate OPT methodology based on patient age and clinical scenario.
Keywords:
Controlled double-blind trialCross reactionFood allergyOral provocation testSingle blind trialopen testserum IgEMore Related Videos
Related Concept Videos
02:20Milgram's Obedience to Authority
6.4K
Obedience to authority is classically demonstrated in a more famous series of social psychology experiments performed by Stanley Milgram. He was a social psychology professor at Yale who was influenced by the trial of Adolf Eichmann, a Nazi war criminal. Eichmann’s defense for the atrocities he committed was that he was “just following orders.”
6.4K
01:17Cochran's Q Test
319
Cochran's Q Test is a nonparametric statistical test used to determine if there are potential differences in the outcomes of three or more related groups on a binary (yes/no) or dichotomous outcome. It is essentially an extension of the McNemar Test, which is limited to two related samples - Cochran's Q test can handle three or more related samples, making it more versatile in scenarios where subjects are measured under multiple conditions. The test statistic follows a Chi-Square...
319
01:23McNemar's Test
234
McNemar's Test is a nonparametric statistical test used to determine if there is a significant difference in proportions between two related groups when the outcome is binary (e.g., yes/no, success/failure). It is beneficial when we have paired data, such as pre-test/post-test designs, where the same subjects are measured under two different conditions. The test is named after the statistician Quinn McNemar, who introduced it in 1947. It is commonly used in situations where subjects are...
234
01:47Aggression
27.8K
Humans engage in aggression when they seek to cause harm or pain to another person. Aggression takes two forms depending on one’s motives: hostile or instrumental. Hostile aggression is motivated by feelings of anger with intent to cause pain; a fight in a bar with a stranger is an example of hostile aggression. In contrast, instrumental aggression is motivated by achieving a goal and does not necessarily involve intent to cause pain (Berkowitz, 1993); a contract killer who murders for...
27.8K