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In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Optimized count-based scintigraphic left ventricular volume measurement
The Canadian Journal of Cardiology
|January 1, 1985
Summary
Optimized scintigraphic left ventricular end-diastolic (LVED) volume measurement offers accurate results, especially for abnormal ventricles. This count-based method may be superior to traditional area-length calculations in cardiac imaging.
Area of Science:
- Cardiovascular imaging
- Nuclear cardiology
- Diagnostic techniques
Background:
- Accurate measurement of left ventricular end-diastolic (LVED) volume is crucial for assessing cardiac function.
- Traditional single-plane contrast ventriculography using the area-length method relies on geometric assumptions that may be inaccurate in cases of abnormal wall motion.
Purpose of the Study:
- To optimize and evaluate a count-based scintigraphic method for measuring LVED volume.
- To compare the accuracy of the optimized scintigraphic method with single-plane contrast ventriculography.
Main Methods:
- Developed a reproducible method for determining left ventricular counts and used an independently measured average apparent tissue attenuation coefficient.
- Calculated tissue depth by triangulation.
- Compared scintigraphic LVED volume measurements with single-plane contrast ventriculography (area-length method) in 18 patients.
Main Results:
- Overall correlation between scintigraphic and ventriculographic LVED volume measurements was high (0.96).
- In patients with normal wall motion, correlation was excellent (0.99) with a small standard error (5.1 ml) and mean absolute difference (3.8 ml).
- In patients with abnormal wall motion, the area-length method showed greater discrepancies, suggesting reduced accuracy.
Conclusions:
- Optimized count-based scintigraphic LVED volume measurement is accurate and reliable.
- This scintigraphic technique may be preferable to single-plane contrast ventriculography for evaluating LVED volume, particularly in ventricles with abnormal wall motion.

