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Published on: March 28, 2025
Acute type A aortic dissection features and outcomes in octogenarians: a propensity score analysis
You Kyeong Park1, Jae Hang Lee1, Kang Min Kim1
1Department of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Octogenarians undergoing surgery for acute type A aortic dissection showed higher rates of certain dissection types but similar early complication and mortality risks compared to younger patients. Age is not a barrier to successful surgical repair in this demographic.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Aortic Disease Research
Background:
- Acute type A aortic dissection (aTAAD) is a life-threatening condition requiring prompt surgical intervention.
- Surgical outcomes in elderly patients, particularly octogenarians (aged 80+), are a significant concern due to potential comorbidities and frailty.
Purpose of the Study:
- To compare the clinical characteristics and early postoperative outcomes of octogenarians versus non-octogenarians undergoing surgical repair for acute type A aortic dissection.
Main Methods:
- A retrospective study included 471 patients who underwent emergency surgical repair for aTAAD between 2003 and 2022.
- Patients were divided into octogenarian and non-octogenarian groups and propensity score matched (1:1 ratio).
- Baseline characteristics, major complications, and 30-day mortality rates were compared between matched groups.
Main Results:
- Octogenarians presented with higher prevalence of DeBakey type II dissection and intramural hematomas, but lower rates of severe aortic regurgitation and aortic root enlargement.
- Postoperative delirium was more frequent in octogenarians (56% vs 25%).
- No significant differences were observed in 30-day/in-hospital mortality, ICU stay, or major complications (stroke, paraplegia, etc.) between the groups after matching.
Conclusions:
- Octogenarians with aTAAD exhibit distinct clinical and imaging characteristics compared to younger patients.
- Advanced age (80+) is not associated with increased early mortality or major complications following surgical repair for acute type A aortic dissection.
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