Related Experiment Video

Updated: Jun 30, 2025

Intratracheal Instillation of Stem Cells in Term Neonatal Rats
04:27

Intratracheal Instillation of Stem Cells in Term Neonatal Rats

Published on: May 4, 2020

5.6K

Hyperbaric oxygen treatment for infants: retrospective analysis of 54 patients treated in two tertiary care centres

Kubra Ozgok Kangal1,2, Bengusu Mirasoglu3

  • 1Department of Underwater and Hyperbaric Medicine, University of Health Sciences, Gulhane Faculty of Medicine, Gulhane Research and Training Hospital, Ankara, Turkey.

Diving and Hyperbaric Medicine
|March 20, 2024
PubMed

Insights

Hyperbaric oxygen treatment (HBOT) is safe and effective for infants, even preterm. This study analyzed outcomes and challenges in pediatric patients receiving HBOT, finding positive results with no reported complications.

Area of Science:

  • Pediatric Medicine
  • Hyperbaric Medicine
  • Critical Care

Background:

  • Hyperbaric oxygen treatment (HBOT) is a medical therapy involving exposure to 100% oxygen at increased atmospheric pressure.
  • Limited data exists on HBOT outcomes and challenges in the pediatric population, particularly in infants.
  • Infants represent a rare patient group for HBOT, necessitating further investigation into its safety and efficacy.

Purpose of the Study:

  • To analyze the outcomes of hyperbaric oxygen treatment (HBOT) in infants (≤12 months old).
  • To describe any difficulties or complications encountered during HBOT in this specific patient population.
  • To evaluate the safety and effectiveness of HBOT for treating various conditions in infants.

Main Methods:

  • Retrospective analysis of 54 infants (≤12 months) who underwent HBOT across two institutions.
  • Data extraction included demographics, clinical presentation, HBOT indications, chamber type, oxygen delivery, treatment count, outcomes, and complications.
  • Analysis focused on identifying trends and safety profiles in infant HBOT.

Main Results:

  • The study included 54 infants with a median age of 3.5 months.
  • Acute carbon monoxide intoxication was the primary indication for HBOT (n=32).
  • Most patients (74%) experienced full resolution of acute signs with no reported HBOT-related complications; only one infant required mechanical ventilation.

Conclusions:

  • Hyperbaric oxygen treatment (HBOT) appears to be a safe and effective therapeutic option for infants.
  • The findings support considering HBOT for indicated conditions in infants, including the preterm age group.
  • Further research is warranted to expand the understanding of HBOT applications in pediatric care.
Abstract

Keywords:
Hyperbaric medicineNeonateNewbornPremature

More Related Videos

Delivery of In Vivo Acute Intermittent Hypoxia in Neonatal Rodents to Prime Subventricular Zone-derived Neural Progenitor Cell Cultures05:45

Delivery of In Vivo Acute Intermittent Hypoxia in Neonatal Rodents to Prime Subventricular Zone-derived Neural Progenitor Cell Cultures

Published on: November 2, 2015

7.3K
A Swine Model of Neonatal Asphyxia10:36

A Swine Model of Neonatal Asphyxia

Published on: October 11, 2011

14.3K

Related Concept Videos

Respiratory Assessment: Purpose and Indications01:19

Respiratory Assessment: Purpose and Indications

Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.1K
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
208
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
137
Hypoxia01:23

Hypoxia

Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
1.0K