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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Related Experiment Video

Updated: Jun 30, 2025

Author Spotlight: Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke
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Author Spotlight: Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

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Computed Tomography Perfusion in Acute Stroke Assessment.

Anthony Pereira1, Vafa Alakbarzade1, Deborah Lowe2

  • 1Department of Neurology, Saint George's University Hospitals National Health Service Foundation Trust, London, UK.

Cerebrovascular Diseases (Basel, Switzerland)
|March 20, 2024
PubMed
Summary
This summary is machine-generated.

CT perfusion (CTP) can help identify more acute ischaemic stroke patients eligible for reperfusion therapy. Integrating CTP into initial stroke imaging protocols may improve treatment access by assessing cerebral vasculature and perfusion.

Keywords:
Acute ischaemic strokeComputed tomography perfusionEndovascular mechanical thrombectomyIntravenous thrombolysisLarge artery occlusionLarge volumeLate window

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Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Traditionally, non-contrast computed tomography (CT) was the primary tool for initial assessment of acute ischaemic stroke, mainly to rule out hemorrhage or other pathologies.
  • Current clinical practice often excludes patients from reperfusion therapy due to insufficient data on cerebral vasculature and perfusion.

Purpose of the Study:

  • To explore the potential benefits of incorporating CT perfusion (CTP) into the initial CT protocol for stroke patient assessment.
  • To evaluate how CTP can improve the identification of patients eligible for reperfusion therapy.

Main Methods:

  • Review of recent large-volume endovascular mechanical thrombectomy (MT) trials.
  • Analysis of CTP imaging's role in guiding MT and intravenous thrombolysis decisions.
  • Exploration of CTP integration into standard initial CT protocols for stroke.

Main Results:

  • Late-window MT trials have integrated CTP to guide treatment decisions.
  • CTP provides crucial data on cerebral vasculature and perfusion, often lacking in standard initial assessments.
  • Incorporating CTP may expand eligibility for reperfusion therapies.

Conclusions:

  • CTP imaging is increasingly vital for guiding reperfusion therapy in acute ischaemic stroke.
  • Integrating CTP into initial stroke assessment protocols can overcome current limitations and improve patient selection for timely treatment.
  • Wider adoption of CTP in acute stroke protocols has the potential to increase the number of patients receiving life-saving reperfusion therapies.