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Updated: Jun 30, 2025

An Integrated Approach for Microprotein Identification and Sequence Analysis
Published on: July 12, 2022
DiGAlign: Versatile and Interactive Visualization of Sequence Alignment for Comparative Genomics
Yosuke Nishimura1, Kohei Yamada2, Yusuke Okazaki2
1Research Center for Bioscience and Nanoscience (CeBN), Research Institute for Marine Resources Utilization (MRU), Japan Agency for Marine-Earth Science and Technology (JAMSTEC).
Abstract:
With the explosion of available genomic information, comparative genomics has become a central approach to understanding microbial ecology and evolution. We developed DiGAlign (https://www.genome.jp/digalign/), a web server that provides versatile functionality for comparative genomics with an intuitive interface. It allows the user to perform the highly customizable visualization of a synteny map by simply uploading nucleotide sequences of interest, ranging from a specific region to the whole genome landscape of microorganisms and viruses. DiGAlign will serve a wide range of biological researchers, particularly experimental biologists, with multifaceted features that allow the rapid characterization of genomic sequences of interest and the generation of a publication-ready figure.
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