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Updated: Jun 30, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Bilateral Hilar and Mediastinal Lymphadenopathy as an Initial Manifestation of Amyloidosis
Mika Urata, Yoko Ito1, Daisuke Ogiya
1Division of Pulmonary Medicine, Department of Medicine,Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan. itoy@tokai.ac.jp.
Abstract:
A 75-year-old male visited our hospital with bilateral hilar lymph node swelling detected on chest radiography during an annual medical checkup. Chest computed tomography revealed swelling of multiple hilar mediastinal lymph nodes. Histopathological and immunohistochemical examinations of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) specimens from the hilar lymph nodes revealed amyloid deposition. Bilateral hilar and mediastinal lymphadenopathies can be the first manifestations of amyloidosis diagnosed using EBUS-TBNA.
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