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Updated: Jun 30, 2025

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
Published on: May 9, 2017
SQANTI3: curation of long-read transcriptomes for accurate identification of known and novel isoforms
Francisco J Pardo-Palacios1,2, Angeles Arzalluz-Luque1,2, Liudmyla Kondratova3,4
1Institute for Integrative Systems Biology, Spanish National Research Council, Paterna, Valencia, Spain.
Abstract:
SQANTI3 is a tool designed for the quality control, curation and annotation of long-read transcript models obtained with third-generation sequencing technologies. Leveraging its annotation framework, SQANTI3 calculates quality descriptors of transcript models, junctions and transcript ends. With this information, potential artifacts can be identified and replaced with reliable sequences. Furthermore, the integrated functional annotation feature enables subsequent functional iso-transcriptomics analyses.
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