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Related Concept Videos

  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. The Potential Value Of Ultrasound In Predicting Local Refractory/relapse Events In Primary Thyroid Lymphoma Patients.
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. The Potential Value Of Ultrasound In Predicting Local Refractory/relapse Events In Primary Thyroid Lymphoma Patients.

Related Experiment Video

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

601

The potential value of ultrasound in predicting local refractory/relapse events in primary thyroid lymphoma patients.

Jiang Ji1,2, Luying Gao1,2, Ruifeng Liu1,2,3

  • 1Department of Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.

Cancer Imaging : the Official Publication of the International Cancer Imaging Society
|March 21, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

Ultrasound features like bilobar enlargement or diffuse type in primary thyroid lymphoma (PTL) predict a higher risk of refractory or relapsed disease. These findings aid in early identification of PTL patients needing closer monitoring.

Keywords:
Primary thyroid lymphomaRefractoryRelapseTreatment outcome

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Area of Science:

  • Oncology
  • Radiology
  • Pathology

Background:

  • Primary thyroid lymphoma (PTL) is a rare malignancy.
  • Ultrasound is crucial for PTL diagnosis and monitoring.
  • Predicting refractory/relapse in PTL is essential but lacks specific ultrasound markers.

Purpose of the Study:

  • To identify sonographic features associated with refractory/relapse events in PTL patients.
  • To improve prognostic assessment for PTL through ultrasound analysis.

Main Methods:

  • Retrospective analysis of 37 newly diagnosed PTL patients from January 2008 to September 2022.
  • Collected clinical and sonographic data before treatment.
  • Compared patients with ideal prognosis versus those with refractory/relapse events.
Ultrasound

Main Results:

  • 37 PTL patients analyzed (26 DLBCL, 2 FL, 9 MALT).
  • Bilobar enlargement (>2.5 cm AP diameter in both lobes) and diffuse ultrasound type correlated with poorer event-free survival (EFS).
  • No significant difference in EFS based on lymph node metastasis, blood signal, or trachea compression.

Conclusions:

  • PTL patients with bilobar enlargement or diffuse ultrasound type are at higher risk for refractory/local relapse.
  • These sonographic findings can aid in predicting PTL treatment outcomes.