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Which Alarm Symptoms Are Associated With Abnormal Gastrointestinal Endoscopy Among Thai Children?
1Department of Pediatrics, Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok, Thailand.
Insights
Hematemesis/hematochezia and low hemoglobin levels are key indicators predicting abnormal pediatric endoscopy results. These alarm symptoms help guide decisions for gastrointestinal endoscopy in children.
Area of Science:
- Pediatric Gastroenterology
- Endoscopic Diagnostics
- Clinical Risk Assessment
Background:
- Alarm symptoms are critical for guiding pediatric gastrointestinal endoscopy.
- Identifying predictive factors for abnormal endoscopic findings is essential for efficient patient management.
Purpose of the Study:
- To identify alarm symptoms and pre-endoscopic investigations that predict abnormal pediatric endoscopy results.
- To determine independent risk factors for abnormal findings in pediatric gastrointestinal endoscopy.
Main Methods:
- Retrospective descriptive study of 148 children under 18 undergoing endoscopy.
- Classification of patients into normal and abnormal endoscopic groups.
- Univariate and multivariate logistic regression analyses to identify risk factors.
Main Results:
- 66 out of 148 participants had abnormal endoscopy results.
- The abnormal group showed a higher prevalence of alarm symptoms, including hematemesis/hematochezia.
- Low hemoglobin, anemia, hypoalbuminemia, elevated ESR, lipase, and BUN/creatinine ratio were significantly higher in the abnormal group.
Conclusions:
- Hematemesis/hematochezia and low hemoglobin levels were identified as independent risk factors for abnormal pediatric endoscopy.
- These findings aid in evaluating alarm symptoms and investigations to predict endoscopic outcomes in children.
Purpose:
Alarm symptoms (red flag signs) are crucial indications for management decisions on pediatric gastrointestinal endoscopy. We aimed to identify items in the alarm symptoms and pre-endoscopic investigations that predict abnormal endoscopy results.
Methods:
A retrospective descriptive study was conducted among children aged under 18 years undergoing endoscopy. The patients were classified into normal and abnormal endoscopic groups. The incidence of alarm symptoms and pre-endoscopic investigations were compared between the groups. Univariate and multivariate logistic regression analyses were performed to determine independent risk factors for abnormal endoscopy.
Results:
Of 148 participants, 66 were classified in the abnormal endoscopy group. Compared with the normal group, the abnormal group had a significantly higher prevalence of alarm symptoms. Moreover, hematemesis/hematochezia, anemia, low hemoglobin level, hypoalbuminemia, rising erythrocyte sedimentation rate, increased serum lipase, and blood urea nitrogen/creatinine ratio were significantly higher in the abnormal endoscopy group than in the normal group. Multivariate logistic regression analysis indicated that hematemesis/hematochezia and low hemoglobin level were independent risk factors for abnormal endoscopy.
Conclusion:
The alarm symptoms and pre-endoscopic investigations were evaluated using predictive factors for abnormal pediatric endoscopic findings. According to multivariate logistic regression analysis, hematemesis/hematochezia and low hemoglobin levels were independent risk factors for abnormal endoscopy.
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