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BRAZILIAN CLINICAL GUIDELINE FOR THE THERAPEUTIC MANAGEMENT OF GASTROESOPHAGEAL REFLUX DISEASE (BRAZILIAN FEDERATION
Joaquim Prado P Moraes-Filho1, Gerson Domingues2, Decio Chinzon1
1Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brasil.
Arquivos De Gastroenterologia
|March 21, 2024
Summary
Updated Brazilian guidelines offer evidence-based management for gastroesophageal reflux disease (GERD). These guidelines focus on proton pump inhibitors (PPIs) and practical clinical application for optimal patient care.
Area of Science:
- Gastroenterology
- Clinical Practice Guidelines
Background:
- Gastroesophageal Reflux Disease (GERD) is a common condition in Brazil, impacting 12-20% of urban dwellers.
- Effective management is crucial due to quality of life implications and potential complications.
- Gastrointestinal specialists utilize guidelines for managing digestive diseases, with the Brazilian GERD guideline being a key resource.
Purpose of the Study:
- To present an updated Brazilian clinical guideline for the therapeutic management of GERD.
- To address recent advancements in knowledge and practice, particularly concerning proton pump inhibitors (PPIs).
- To provide practical, evidence-based recommendations for healthcare professionals in Brazil.
Main Methods:
- Extensive literature review across multiple languages and databases (Medline, Embase, SciELO-Lilacs).
- Focus on systematic reviews and meta-analyses concerning GERD and PPIs.
- Utilized the PICO system for question formulation and the GRADE system for evidence and recommendation grading.
Main Results:
- Guidelines are presented in a user-friendly question-and-answer format.
- Recommendations are supported by robust scientific evidence and expert opinions.
- The GRADE system clarifies evidence quality (high to very low) and recommendation strength (strong to conditional).
Conclusions:
- The updated guidelines provide practical, evidence-based advice for GERD management in Brazil.
- Aims to equip healthcare professionals with the latest knowledge for optimal patient care.
- Emphasizes the critical evaluation of PPIs, including safety and appropriate use.
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