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Updated: Jun 30, 2025

Characterization of Immune Cells and Proinflammatory Mediators in the Pulmonary Environment
Published on: June 24, 2020
[Research progress of CD93+ B lymphocyte subsets in inflammation and inflammation related diseases]
Changping Niu1, Siyu Sun2, Dongyan Liu3
1Department of Medical Research Center, Shengjing Hospital of China Medical University, Shenyang 110004, China.
Insights
CD93 is a molecule found on immature B cells that plays a role in cell movement and adhesion. Detecting CD93-positive B cells aids in diagnosing and monitoring inflammatory diseases.
Area of Science:
- Immunology
- Cell Biology
Abstract:
CD93 is expressed in progenitor B (pro-B) cells, precursor B (pre-B) cells and various immature B cells. It can interact with moesin, MMRN2 and other molecules to participate in cell migration, adhesion and phagocytosis, so it plays an important role in inflammation and angiogenesis. Detection of CD93+ B cell subsets has a crucial role in the diagnosis, treatment and prognosis monitoring of inflammation and inflammation-related diseases, such as Helicobacter pylori-related gastritis, sepsis, non-obese diabetes and periodontitis.
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