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Updated: Jun 27, 2026

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The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
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Symbol Digit Modalities Test in progressive multiple sclerosis.
Bartosz Gajewski1, Iwona Karlińska1, Mariusz Stasiołek2
1Department of Neurology, Medical University of Lodz, Lodz, Poland.
Neurologia I Neurochirurgia Polska
|March 21, 2024
Summary
The Symbol Digit Modalities Test (SDMT) effectively assesses information processing speed (IPS) in progressive multiple sclerosis (PMS). This valuable tool aids neurologists in diagnosing cognitive deficits common in PMS patients.
Area of Science:
- Neuropsychology
- Neurology
Background:
- The Symbol Digit Modalities Test (SDMT) is a sensitive tool for assessing information processing speed (IPS).
- Its application in progressive multiple sclerosis (PMS) requires focused evaluation.
Purpose of the Study:
- To review the current knowledge on SDMT use in evaluating primary progressive multiple sclerosis (PPMS) and secondary progressive multiple sclerosis (SPMS) patients.
- To explore the relationship between disease factors and SDMT performance in PMS.
Main Methods:
- A comprehensive literature review was conducted.
- Focus was placed on studies evaluating SDMT in PPMS and SPMS subtypes.
- Disease-associated factors like disease course, imaging, biomarkers, and treatment were analyzed in relation to SDMT.
Main Results:
- SDMT is a valuable and accessible instrument for assessing cognitive function in neurological disorders.
- IPS deficits are more prevalent in PMS patients compared to relapsing-remitting MS or healthy individuals.
- Disease course, imaging findings, biomarkers, and treatment influence SDMT performance in PMS.
Conclusions:
- SDMT is highly useful for neurologists and neuropsychologists, particularly for evaluating PMS.
- Further research with larger cohorts is needed to differentiate cognitive assessment across PMS subtypes.
Keywords:
SDMTSymbol Digit Modalities Testcognitive dysfunctioninformation processing speedprogressive multiple sclerosisMore Related Videos
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