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Updated: Jun 14, 2026

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate HoLEP.
Published on: March 6, 2018
Transurethral bipolar enucleation using a TUEB loop for large benign prostatic hyperplasia: a retrospective cohort
Jun Hagiuda1, Tsukasa Masuda2, Ryohei Takahashi2
1Department of Urology, Tokyo Dental College, Ichikawa General Hospital, Sugano 5-11-13, Ichikawa, Chiba, 2728513, Japan. hagiudaj@tdc.ac.jp.
Transurethral enucleation with bipolar system (TUEB) is effective and safe for benign prostatic hyperplasia (BPH) surgery, regardless of prostate size. This TUEB loop technique offers high enucleation efficiency, making it a top choice for managing large prostates.
Area of Science:
- Urology
- Minimally Invasive Surgery
- Surgical Technology
Background:
- Benign prostatic hyperplasia (BPH) affects a significant number of aging men.
- Transurethral enucleation with bipolar system (TUEB) is a common surgical treatment for BPH.
- Prostate size can influence the choice and outcomes of surgical interventions.
Purpose of the Study:
- To evaluate the efficacy and safety of transurethral enucleation with bipolar system (TUEB) using a specialized loop.
- To assess TUEB performance irrespective of prostate volume (PV).
Main Methods:
- A cohort of 251 patients undergoing TUEB was divided into small-PV (≤80 mL) and large-PV (>80 mL) groups.
- Comparative analysis of demographic data and treatment outcomes between the two groups.
- Assessment of operative times, enucleation efficiency, and functional outcomes.
Main Results:
- While operative, enucleation, and morcellation times were longer in the large-PV group, enucleation efficiency and PSA reduction rates were superior.
- Both groups showed significant improvements in International Prostate Symptom Score, maximum flow rate, and post-void residual urine at 12 months.
- No blood transfusions were required, and complication rates (clot retention, urethral stricture, incontinence) were similar between groups.
Conclusions:
- TUEB with the specialized loop demonstrates high satisfaction, efficiency, and safety for BPH surgery across all prostate sizes.
- TUEB is a highly recommended surgical option for large BPH cases unresponsive to medication.
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