Stage of diagnosis and survival for prostate cancer among immigrant men in Ontario, Canada
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View abstract on PubMed
Summary
This summary is machine-generated.Prostate cancer patients who immigrated to Ontario, Canada, were more often diagnosed early and had better survival rates. Immigrants from the Caribbean and Sub-Saharan Africa showed the greatest benefits, while South Asian men had the least advantage.
Area Of Science
- Oncology
- Epidemiology
- Public Health
Background
- Previous studies identified higher prostate cancer incidence in West African and Caribbean immigrant groups in Ontario.
- This study investigates diagnostic stage and survival outcomes for prostate cancer among diverse immigrant populations in Ontario.
Purpose Of The Study
- To compare prostate cancer diagnosis stage, 5-year overall survival, and prostate cancer-specific survival between immigrants and long-term residents in Ontario.
- To identify specific immigrant groups with differential outcomes.
Main Methods
- Population-level retrospective cohort study using linked administrative databases in Ontario.
- Included male residents aged 20-105 with incident prostate cancer (March 2008-March 2017).
- Multivariable logistic regression and Kaplan-Meier curves were used to analyze diagnostic stage and survival, adjusting for covariates.
Main Results
- Immigrants from West Africa, East Africa, and the Caribbean had a higher likelihood of early-stage prostate cancer diagnosis compared to long-term residents.
- South Asian men were most likely to be diagnosed at a late stage.
- Overall and prostate cancer-specific survival rates were higher for immigrants than long-term residents, with Caribbean and Sub-Saharan African men showing the best survival, and South Asian men the lowest.
Conclusions
- Immigrant men in Ontario diagnosed with prostate cancer benefit from earlier diagnosis and improved 5-year survival compared to long-term residents.
- Significant variations exist among immigrant groups, with Caribbean and Sub-Saharan African men demonstrating superior outcomes.
- Potential contributing factors include awareness, diagnostic practices, genetics, and social determinants of health.
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