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Unrelenting Infection of Implanted Prosthetic Hip Joint by Corynebacterium striatum

Supriya Sachan1, Aayushi Dhawan1, Vivek Jangira2

  • 1Microbiology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohla Hospital, New Delhi, IND.

Cureus
|March 22, 2024
PubMed

Insights

Non-diphtherial Corynebacterial (NDC) species are emerging opportunistic pathogens. This case highlights a multidrug-resistant Corynebacterium striatum infection in a hip replacement, emphasizing infection prevention.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Orthopedic Surgery

Background:

  • Non-diphtherial Corynebacterial (NDC) species were historically dismissed as contaminants.
  • Increasingly, NDC are recognized as significant opportunistic pathogens in clinical settings.

Observation:

  • A case of a non-healing infection involving implanted devices in bilateral total hip replacement is presented.
  • The infection was caused by multidrug-resistant Corynebacterium striatum.

Findings:

  • Corynebacterium striatum can cause persistent and difficult-to-treat prosthetic implant infections.
  • Multidrug resistance in NDC poses a significant challenge for therapeutic interventions.

Implications:

  • Clinical significance of NDC, particularly in immunocompromised patients or those with implants, should be carefully evaluated.
  • Strict adherence to infection prevention strategies is crucial for preventing prosthetic implant infections.
  • Further research into effective treatment strategies for multidrug-resistant NDC infections is warranted.
Keywords:
anti-microbial agentsbiofilmcorynebacterium striatumgram positive bacilliimplanted devicesinfection prevention strategiesmultidrug resistantnon-healing infection prosthetic joint infectionvirulence factors

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