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Pancreatic Extragastrointestinal Stromal Tumor: A Case Report
Tianyu Song1, Qiang Hong1, Yulian Wu1,2
1Department of Surgery, Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, CHN.
Cureus
|March 22, 2024
Summary
Extra-Gastrointestinal Stromal Tumors (EGISTs) are rare sarcomas found outside the GI tract. This case highlights a pancreatic EGIST in a 51-year-old woman, confirmed via surgery and immunohistochemistry.
Area of Science:
- Gastroenterology and Oncology
- Surgical Pathology
Background:
- Gastrointestinal stromal tumors (GISTs) arise from mesenchymal cells within the GI tract.
- Extra-GISTs (EGISTs) represent rare GISTs originating from extragastrointestinal sites.
Observation:
- A 51-year-old woman presented with a pancreatic mass.
- Enhanced CT revealed a lesion in the pancreatic head and duodenum.
- Routine tests were normal, but imaging suggested a pancreatic mass.
Findings:
- Laparoscopic surgery was performed.
- Histopathological and immunohistochemical analysis confirmed an EGIST.
- The tumor was positive for CD117, CD34, and DOG1, indicating a high malignancy risk.
Implications:
- This case expands the known locations for EGISTs.
- Early diagnosis and surgical management are crucial for high-risk EGISTs.
- Long-term follow-up is necessary to monitor for recurrence.
