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Polymyalgia Rheumatica Post-SARS-CoV-2 Infection.

Carolina Duarte-Salazar¹, José Eugenio Vazquez-Meraz², Lucio Ventura-Ríos¹

¹Departmento de Reumatología, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Mexico City, Mexico.

Case Reports in Immunology

|March 22, 2024

Summary

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can trigger autoimmune responses. This case highlights polymyalgia rheumatica as a rare post-COVID-19 rheumatic manifestation, successfully treated with prednisone.

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Area of Science:

Rheumatology
Infectious Diseases
Immunology

Background:

Growing evidence links SARS-CoV-2 infection to immune dysregulation and autoimmune phenomena.
Post-viral syndromes can manifest with diverse rheumatological symptoms.

Observation:

A 75-year-old woman presented with acute neck and shoulder pain, stiffness, and fatigue post-COVID-19.
Clinical presentation and ultrasound revealed bilateral subacromial-subdeltoid bursitis, initially suggestive of polymyalgia rheumatica (PMR).

Findings:

Despite negative C-reactive protein, symptoms aligned with PMR criteria.
Treatment with prednisone led to complete recovery within six months.

Implications:

COVID-19 infection may precipitate autoimmune rheumatic conditions like PMR.
PMR should be considered in the differential diagnosis of rheumatological symptoms following SARS-CoV-2 infection.