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Updated: Jun 30, 2025
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Acute lymphoblastic leukemia with pseudo-Chediak-Higashi granules in the initial diagnosis and relapse
Rongjie Li1, Shimei Xia1, Yingyan Liao1
1Department of Laboratory Medicine, Kumming Children's Hospital, Kumming, Yunnan, China.
Abstract:
Pseudo-Chediak-Higashi granules are large cytoplasmic inclusions commonly encountered in myeloblasts or other myeloid precursors in acute myeloid leukemia and myelodysplastic syndromes. However, pseudo-Chediak-Higashi granules are rarely found in acute lymphoblastic leukemia (ALL). We present the case of an 8-year-old boy who was diagnosed with ALL with pseudo-Chediak-Higashi granules in the initial diagnosis and relapse, acting like a characteristic marker.
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